Posted on 2/4/2019
Patients with dengue fever, a mosquito-borne illness that causes a severe flu-like condition, typically start out with similar symptoms, but as the disease progresses, some wind up with life-threatening infections, while others mend fine on their own. So far, it's been challenging for doctors and scientists to predict who will come down with "severe dengue," and who will walk away unscathed.
Now, in search of a solution to that problem, Purvesh Khatri, PhD, associate professor of medicine and of biomedical data science, and Shirit Einav, MD, associate professor of medicine and of microbiology and immunology, have reanalyzed previously-published dengue patient data, discovering a key set of genes whose expression can predict who will suffer severe dengue. As ...