Chromatography Resin Improves Speed, Flexibility

MilliporeSigma’s Eshmuno CP-FT chromatography resin uses flow-through frontal chromatography to remove aggregates from mAb therapeutics, which can induce an immunogenic response in patients.

By enabling loading capacities 10 times higher than traditional bind/elute CEX chromatography, the resin reduces costs and improves productivity. It requires less resin and less buffer volume while offering a shorter processing time. Low salt process conditions eliminate the need for dilution before subsequent ion exchange steps. The resin offers a significant reduction in processing volumes improves virus filtration and ultrafiltration processing economics. Its rigid base bead enables higher flow rates and easier column packing.