APPNOTE-Accurate tracking of chemotactic cancer cell migration
Basic insights in metastasis
Chemotaxis is the movement of cells along a chemoattractant gradient. Here, the authors of the study aimed to determine the effect of a fetal bovine serum (FBS) gradient on directed migration of cancer cell lines using side-by-side live-cell imaging with the CytoSMART® Lux3 BR Duo Kit. This revealed the chemotactic migration of HeLa cells under the FBS gradient, whereas C6 glioma cells displayed no clear chemotactic migration. The high-quality imaging and corresponding results can be relevant to fundamental research on cancer metastasis.