What blood tests are done for bleeding disorders?

Coagulation, Thrombosis, Hemostasis

The tests required for hemorrhagic diseases include physical examination, laboratory examination, quantitative immunologic test, chromosome and genetic test.

I. Physical examination

Observation of the location and distribution of bleeding, whether there is hematoma, petechia and eccechia, as well as whether there are signs of related diseases such as anemia, enlarged liver and splenic lymph nodes, urticaria, can be conducive to the preliminary diagnosis of whether it is a type of blood disease and the subsequent selection of appropriate treatment.

II. Laboratory tests

1. Blood routine examination: according to the number of platelets and the content of hemoglobin, we can understand the degree of platelets reduction and the situation of anemia.

2. Blood biochemical examination: according to serum total bilirubin, indirect bilirubin, serum bound eggs and LDH, understand the jaundice and hemolysis.

3. Coagulation test: to understand whether there is any abnormality in the blood clotting function according to the plasma level of fiber protein, D-dimmer, degradation products of fiber protein, the complex of clotin-Anti-trombin, and the inhibitor of Plasmin-activating factor.

4. Marrow cell examination: to understand the changes of red blood cells and granulose cells, find out the causes, and distinguish them from other blood system diseases.

III. Immunological quantitative analysis

To assess the level of platelets and clotting factor related antigens and antibodies.

IV. Chromosome and gene analysis

Patients with certain genetic defects can be diagnosed by FISH and genetic testing. FISH is used to determine whether there are known types of gene mutation, and gene testing is used to screen for specific mutation of genetic diseases.

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