What is the coagulation process?

Coagulation, Thrombosis, Hemostasis

Blood coagulation is the process in which coagulation factors are activated in a certain order, and finally fibrinogen is converted into fibrin. It is divided into the intrinsic pathway, the exogenous pathway and the common coagulation pathway.

The coagulation process can be divided into three stages: the formation of prothrombin activator, the formation of thrombin and the formation of fibrin. When a small blood vessel is punctured and causes bleeding in the body, the damaged blood vessel contracts first, shrinking the wound, slowing blood flow, and aggregating coagulation substances. The local blood viscosity will increase, which is conducive to hemostasis. The exposure of the subendothelial components of the blood vessels causes platelet activation, adhesion, aggregation and release reactions, and the formation of platelet thrombi locally to block the wound.

At the same time, the exposed subendothelial components activate factor XII to start the intrinsic coagulation pathway, release tissue factors to start the exogenous coagulation pathway, and finally form fibrin thrombi, blocking the wound and completing coagulation. Among them, the factors involved in intrinsic coagulation are factors VIII, IX, X, XI, and XII, the factors involved in exogenous coagulation are factors III and VII, and the coagulation factors involved in the common pathway are factors I, II, IV, V, and X. These factors work together to complete the blood coagulation process.

Company Introduction

Beijing Succeeder Technology Inc. (Stock code: 688338), founded in 2003 and listed since 2020, is a leading manufacturer in coagulation diagnostics. We specialize in automated coagulation analyzers and reagents, ESR/HCT analyzers, and hemorheology analyzers. Our products are certified under ISO 13485 and CE, and we serve over 10,000 users worldwide.

Analyzer Introduction

Fully Automated Coagulation analyzer SF-9200 (https://www.succeeder.com/fully-automated-coagulation-analyzer-sf-9200-product) can be used for clinical test and pre-operative screening. Hospitals and medical scientific researchers also can use SF-9200. Which adopts coagulation and immunoturbidimetry, chromogenic method to test the clotting of plasma. The instrument shows that clotting measurement value is the clotting time (in seconds). If the test item is calibrated by calibration plasma, it can also display other related results.

The product is made of sampling probe movable unit, cleaning unit, cuvettes movable unit, heating and cooling unit, test unit, operation-displayed unit, LIS interface (used for printer and transfer date to Computer).

Technical and experienced staffs and analyzers of high quality and strict quality management are the guarantee of manufacture of SF-9200 and good quality. We guarantee each instrument inspected and tested strictly. SF-9200 meets China national standard, industry standard, enterprise standard and IEC standard.