Which enzyme causes blood to clot?

Coagulation, Thrombosis, Hemostasis

The coagulation process is relatively complex and involves the participation of multiple enzymes, among which thrombin is a key thrombin.

Basic information:

Thrombin is a serine protease that plays a core role in the coagulation process. It is mainly activated and transformed by prothrombin under the action of coagulation factor ⅩⅢa and calcium ions.

Coagulation mechanism:

Thrombin can act on fibrinogen to convert it into fibrin monomers. Fibrin monomers polymerize with each other to form insoluble fibrin polymers, which then cross-link to form a stable fibrin network, entrapping blood cells such as platelets and red blood cells to form blood clots and achieve the purpose of coagulation. At the same time, thrombin can also activate platelets, causing them to aggregate and release multiple coagulation factors, further promoting the coagulation process.

In addition to thrombin, there are some enzymes that also play an important role in the coagulation process, such as coagulation factor ⅩⅢa, etc. They work together to ensure the smooth progress of the coagulation process.

Beijing Succeeder Technology Inc. (Stock code: 688338), founded in 2003 and listed since 2020, is a leading manufacturer in coagulation diagnostics. We specialize in automated coagulation analyzers and reagents, ESR/HCT analyzers, and hemorheology analyzers. Our products are certified under ISO 13485 and CE, and we serve over 10,000 users worldwide.

Analyzer Introduction

Fully Automated Coagulation analyzer SF-9200 (https://www.succeeder.com/fully-automated-coagulation-analyzer-sf-9200-product) can be used for clinical test and pre-operative screening. Hospitals and medical scientific researchers also can use SF-9200. Which adopts coagulation and immunoturbidimetry, chromogenic method to test the clotting of plasma. The instrument shows that clotting measurement value is the clotting time (in seconds). If the test item is calibrated by calibration plasma, it can also display other related results.

The product is made of sampling probe movable unit, cleaning unit, cuvettes movable unit, heating and cooling unit, test unit, operation-displayed unit, LIS interface (used for printer and transfer date to Computer).

Technical and experienced staffs and analyzers of high quality and strict quality management are the guarantee of manufacture of SF-9200 and good quality. We guarantee each instrument inspected and tested strictly. SF-9200 meets China national standard, industry standard, enterprise standard and IEC standard.