Malvern Panalytical company News and Trends items

X-ray diffraction (XRD) technique is an important non-destructive material characterization analytical tool for investigating condensed matter in powder, single crystal and thin film forms. From research to production, XRD is an indispensable technique for material characterization providing detailed information about the internal lattice of crystalline substances. In ord...

In this masterclass series, we’ve introduced you to a few techniques for measuring particle size. In this webinar, we’ll focus on laser diffraction and analytical imaging and how to develop methods for these techniques to ensure you get the best results. There are three key areas to method development; sampling, dispersion, and the instrument setup. In this webinar we’ll...

Conducting proper solid form analysis is a very important part of the daily routine in the pharmaceutical research and industry. Being one of the most powerful methods of solid form characterization, X-ray Powder Diffraction (XRPD) allows in the Early Development stage not only to select the most promising lead candidates for the Active Pharmaceutical Ingredient (API), b...

The highly successful Empyrean X-ray diffractometer just got better with an all-new detector. The detector provides a leapfrog increase in system capability and it is about to take X-ray diffraction to the next level when launched on the 27th of August. Dramatically improving performance for all powder diffraction applications, the detector opens up a new world for wo...

Approach early-stage drug discovery armed with greater insight, by using the advanced isothermal titration microcalorimetry (ITC) capabilities of the MicroCal PEAQ-ITC. Find out how ITC is being successfully applied to study enzyme kinetics and enzyme inhibition. Discover how to refine your experiments and workflows to generate meaningful data quickly and gain deeper...

While the advantages of Orally Inhaled and Nasal Drug products for both systemic and locally acting drug delivery are widely understood, the challenge remains to develop products with the required performance. The property of the formulation, the design of the delivery device and the actuation characteristics of the target user group all influence dispersion behavior ...

The challenges of differentiated drug product development, increased pressure from generic products, and low rates of return on development costs are all factors driving pharmaceutical companies to seek strategies to accelerate and de-risk their product development. Their ultimate aim is a more rapid realization of pipeline value. Key to their success is a data-driven...

How can the development viability of a new drug product or formulation be assessed? In response to the challenges associated with developing complex pharmaceutical products, the US FDA and other worldwide regulators have released product-specific guidance advising on the in vitro methods which can be applied to assess bio-availability. Targeted at enabling the rapid deve...

The Mastersizer 2000 has been embraced by many research and industrial customers for checking the performance of their products. Whether it is for monitoring the stability of APIs or excipients, to testing the strength of cement fines to understanding the deterioration of catalysts. With the Mastersizer 2000 approaching its end of life, we want to use this transition per...

The beauty of working in the research and development team is to be able to look into the future and anticipate needs that our end users did not even realize they required before. Malvern Panalytical is proud to announce our latest version of the HighScore Plus software, version 4.9. Ever since its conceptualization, our software developers have made improvements such as...

Safe manufacture and supply of pharmaceutical products requires companies to ensure that patient exposure to toxic elements such as lead (Pb), mercury (Hg), arsenic (As) and cadmium (Cd) is controlled to within safe limits as part of their drug dosing regimens. In response to this need, the International Conference on Harmonization (ICH) issued guidance in ICH Q3D regard...

The OMNISEC Virtual User Meeting will offer participants a chance to hear from others in the OMNISEC community, as well as your favorite Malvern Panalytical scientists, as they discuss OMNISEC and the valuable data it provides. The content will focus on multi-detector GPC/SEC data, how the various combinations of detectors work together to provide calculated characteriza...

Solid form analysis plays a vital role in materials characterization throughout the pharmaceutical development cycle. X-ray Powder Diffraction (XRPD), one of the solid form analysis methods, is a comprehensive technique which is used to ensure that a product meets its target performance profile. In the early stages (Discovery and API Development), XRPD is an importan...

Over the past decades, an emerging number of nanomedicines was applied in cancer therapy. Following intravenous administration, highly advanced therapeutics such as liposomes and polymeric nanoparticles change the distribution of compounds in the human body and lead to a significant reduction of the side effects of cytostatic drugs. Pharmacokinetic analysis plays a k...

Have you ever wondered, what are the main differences and similarities between Laser Diffraction and Dynamic Light Scattering? Perhaps you have come across a sample for which you are not sure what technique will provide the most accurate particle size results? Laser Diffraction and Dynamic Light Scattering are extremely popular particle sizing techniques that together...

Elemental composition results from x-ray fluorescence instruments are used to make decisions affecting your operation and business. Malvern Panalytical is committed to helping you achieve the utmost confidence in your results. Whether to help settle a discussion with your own customers, pass a lab accreditation audit or to be 21 CFR part 11 compliant, in this webinar we ...

Find out how Amplify Analytics can help accelerate your workflow Join our upcoming webinar “Amplify Analytics: Integrating chemistry and physicochemical analysis for rapid pharmaceutical development”. Amplify Analytics is a new service from Malvern Panalytical and Concept Life Sciences. Together we can help pharmaceutical leaders like you identify and implement th...

In this webinar, we will focus on the measurement reproducibility and repeatability we can expect from the Zetasizer Ultra’s multi-angle dynamic light scattering (MADLS) based particle concentration, when we are using it to measure AAV samples. We will investigate whether the technology used or the samples themselves have the greatest impact! You can register for free...

Over the last twenty years or so, laser diffraction has emerged as a widely accepted technique for particle size analysis across different segments. The various advantages of the technique like wide dynamic range, high sample throughput, the robustness of results and regulatory acceptancy make it popular in both the R+D environment and QC departments. The webinar series ...

Throughout 2020 we’ve had a program of events to guide you through transferring methods from the Mastersizer 2000 to the Mastersizer 3000. Previous webinars have talked you through the process and shown you some case studies from a few customers who’ve been through it already. Now it’s time to put what we’ve been talking about into practice. Join us from our applicati...

Do you want to know more about setting up methods and analyzing data with the Morphologi? Are you interested in using the system for size, shape and chemical characterization or quality management of your products? Would you like to hear other users’ stories of success? If yes, please come join us on June 23rd, 2020, for a virtual Morphologi 4 & 4ID user meeting. ...

Over the last twenty years or so, laser diffraction has emerged as a widely accepted technique for particle size analysis across different segments. The various advantages of the technique like wide dynamic range, high sample throughput, the robustness of results and regulatory acceptancy make it popular in both the R+D environment and QC departments. This webinar is...

Setting meaningful and realistic specifications for pharmaceutical product Critical Material Attributes (CMAs) is an important in ensuring a product meets its target performance profile. Within this, the polymorphism and crystallinity of the Active Pharmaceutical Ingredients (APIs) and excipients present within a product formulation are crucial. The presence of an undesi...

Setting meaningful and realistic specifications for pharmaceutical product Critical Material Attributes (CMAs) is an important in ensuring a product meets its target performance profile. Within this, the polymorphism and crystallinity of the Active Pharmaceutical Ingredients (APIs) and excipients present within a product formulation are crucial. Presence of an undesired ...

A wide variety of materials with very different properties are utilized in the field of paints and coatings. Among these are pigments for use in both wet and dry paint applications, where size and shape govern the optical properties from opacity (e.g. titanium dioxide), to flip/flop for metallic and mica materials. In dry systems (powder coatings) powder flow is key and ...

In this short webinar we will be looking more closely at why %CV of particle concentration measurements vary more when there are aggregates present in the sample. We will look at how the calculation of concentration from a multi-angle dynamic light scattering (MADLS) measurement in a Zetasizer Ultra is performed and identify the factors that may affect the repeatabili...

X-ray diffraction is one of the most powerful tools for identifying unknown crystalline phases. And there are various databases that crystallographers can reference against, for instance ICDD. By comparing the positions and intensities of the diffraction peaks against a library of known crystalline materials, the target material can be identified. This action is known as...

Dynamic light scattering (DLS), also known as photon correlation spectroscopy (PCS) and quasi-elastic light scattering (QELS), is a technique used to measure the Brownian motion (diffusion) and subsequent size distribution of an ensemble collection of particles in solution. For a collection of solution particles illuminated by a monochromatic light source, the scattering...

This webinar series considers the requirements for elemental analysis of pharmaceutical intermediates and final dosage forms using X-Ray Fluorescence (XRF). In the first webinar, we discussed the position of XRF in this application, and in the second, we performed a live demonstration of the analytical workflow. In this third webinar, we will discuss a case study done ...

X-ray diffraction is one of the most powerful tool for identifying unknown crystalline phases. Many considerations and implications rest on the XRD results collected in terms of designing better materials or making decisions on your process control. What would your conclusions be if you notice peak shifts or peak broadening in your sample? During our work with numerous c...

Malvern Panalytical, one of the world’s leading suppliers of analytical instrumentation and software, opened their APAC Application Center of Excellence in Shanghai on May 22nd. President of Malvern Panalytical addresses the news via live video. After further expansion and upgrading, Malvern Panalytical’s APAC Application Center of Excellence opened within the Malvern...

I was recently thinking over the recent guidance on social distancing during the current COVID-19 pandemic. Advice from health professionals and Government advisors suggests a 2-meter distance is required to limit the spread of the Coronavirus, as it is unlikely that droplets from a cough or a sneeze will travel further. This made me think, as a scientist who is somewhat...

The last webinar in this series will elaborate on the value of Nanoparticle Tracking Analysis (NTA) to the development of vaccines, including the characterization of VLPs (several Virus Like Particles being developed as vaccines to COVID19). More than a simple particle size analysis, the ability to rapidly make total (not just infective) particle concentration measur...

Dynamic Light Scattering (DLS), sometimes referred to as Photon Correlation Spectroscopy or Quasi-Elastic Light Scattering, is a technique classically used for measuring the size of particles typically in the sub-micron region, dispersed in a liquid. In vaccine and bio-formulations, understanding the stability of biological molecules is critical towards ensuring their...

Drug product developers face many challenges as they seek to develop new drug products based on novel dosage forms or delivery technologies. This particularly true of Orally Inhaled and Nasal Drug Products (OINDPs), where developers must not only develop an effective formulation but also understand how this can be reproducibly delivered to a patient using a complex devic...

Have you ever wondered if all particles are really spherical? Or what extra insight you might get from measuring particle shape as well as particle size? Techniques like laser diffraction provide rapid particle size measurement but achieve this through assuming that the measured particles are spherical. This is often enough for the needs of product quality control. Ho...