Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide

One class of small molecules that lead to many treatments now providing standard of care for cancer patients are kinase inhibitors. This target class contains over 500 members, many of which are undrugged. Protein kinase inhibitors are anticipated to deliver many more therapies to treat cancer and other diseases, such as fibrosis and rheumatoid arthritis. Small molecule...

Immunotherapy is a powerful tool in the targeted treatment of a wide range of disease pathologies and the number of immunotherapy drugs in the discovery pipeline continues to grow. Immunotherapy approaches include switching off or restoring balance to aberrant immune responses (such as those seen in autoimmune disease or allergy) or switching on beneficial immune respons...

There’s always more to learn, whether it’s setting up your measurements for quick batch processing, gaining confidence in the quality of your results, or presenting your data in the best format. For this webinar, we’ll assume you’ve watched the previous one on the same topic. Don't worry if you missed it or can't remember it – you can watch it back here. Don’t forget ...