Modelling Nanomedicines: Unchain your pharmacokinetic analysis for in vivo data

Live Webinar, July 14th, 2020

Over the past decades, an emerging number of nanomedicines was applied in cancer therapy. Following intravenous administration, highly advanced therapeutics such as liposomes and polymeric nanoparticles change the distribution of compounds in the human body and lead to a significant reduction of the side effects of cytostatic drugs.

Pharmacokinetic analysis plays a key role in evaluating the performance of formulations. However, the traditional non-compartmental and compartmental modeling approaches often do not enable the in vivo behavior of nanomedicines to be correlated to the physicochemical and in vitro characteristics.

This talk is delivered by Dr. Matthias Wacker, who is an Associate Professor with the National University of Singapore’s Pharmacy department. He provides an outline of the latest methodologies in analyzing the pharmacokinetics of nanocarrier formulations with a clear perspective towards in vitro-in vivo correlations. Dr. Wacker is joined by Malvern Panalytical’s nanomatrics application specialist, Dr Anand Tadas. Together, they will open a dialogue about the opportunities in analyzing and re-analyzing the in vivo data. And importantly, how to gain a deeper insight into the applications using nanoparticle tracking analysis (NTA).

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