Diffraction in drug development

Live webinar 25 January 2022

Controlling solid form is a key concern from the moment lead compounds are crystallized, all the way through to commercial manufacture. And as a lead becomes a candidate molecule, it’s important to understand how its particles are distributed and how they behave. The particle size distribution and purity of an API are often controlling factors in how it moves, packs and dissolves – and this, in turn, can impact the final drug product’s bioavailability, efficacy, and even its safety.

Consequently, solid form and particle size distribution are critical material attributes that must be measured and controlled. X-ray diffraction and laser diffraction are used for this purpose. They provide complementary information on particle size and crystallo-chemical composition.

In this webinar, we will discuss:

the fundamental differences between X-ray diffraction and laser diffraction

the insights provided by these two techniques

guidance for method development for both XRD and LD particle sizing

We’ll also show you how Malvern Panalytical and Concept Life Sciences can support these activities in your drug development workflows.

You can register for free to all our webinars and you will automatically receive the On-Demand version