Mantra™ quantitative pathology workstation with inForm® image analysis software enables easy visualization, quantification and phenotyping of multiple types of immune cells simultaneously in intact FFPE tissue sections for cancer immunology research.
Mantra is a compact workstation where a researcher can phenotype immune cells in situ in solid tumors using multiplexed biomarkers. Unlike existing flow cytometry and next generation sequencing methods which can phenotype and quantify immune cells in homogenized samples, Mantra similarly does this using images of FFPE tissue sections, while maintaining tissue architecture and morphology. This provides spatial information which could lead to a better understanding of the role and types of immune cells within both the tumor and the tumor microenvironment so that new cancer immunotherapy treatments may be identified and researched.
The Mantra is an integrated workstation incorporating multispectral imaging technology, novel image acquisition and inForm analysis software. It can be used with a variety of stains including PerkinElmer's Opal™ reagent kits. The Mantra system is a part of PerkinElmer’s cancer immunology portfolio which includes staining reagents, imaging systems, and image analysis software.