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Keywords: Cerebellum, Circadian Clock gene, Corticosterone, Suprachiasmatic nucleus, iPRECIO programmable micropump

In this case, however, the researchers used the pump to emit carefully metered doses of corticosterone at different times of the day and night, similar to the animals' natural rhythm.” from

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Original Stone Ln, Eufaula, OK 74432, USA

Tokyo

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Application of iPRECIO from peer reviewed publications

How iPRECIO pumps were used/programmed

Tabular highlights gives a high level view of how iPRECIO pumps were used/programmed in selected scientific publications in Applications Examples eBook. For more detailed view, refer eBook and publications . In e-book for example, Research Application 1 (RA1) on page 5 & 6 of eBook is on row 1 of Tabular highlights – Chavan et al. The protocol is once a day infusion. RA2...

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Programmable Pumps for Compound Delivery in Oncology Research

In this webinar, Christian will describe the validation studies performed in his pharmacology unit with iPRECIO pumps implanted in rats and mice.

In oncology drug discovery programs, modulating target engagement via drug-delivery technologies can enable pivotal pharmacological studies. Over the past decade, there is increasing interest in establishing a robust mechanistic understanding of the pharmacokinetics–pharmacodynamics (PK–PD) relationship of a given compound and its connection to the anti-tumor efficacy pr...

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iPRECIO Programmable Minipumps for continuous delivery lenalidomide (LLD) in chronic lymphocytic leukemia (CLL).

Rodent Studies of PK, Safety and Tolerability of LLD in Healthy and SCID Mice by Dr Jamie Oliver Chief Medical Officer of Starton Therapeutics

iPRECIO Programmable Minipumps for continuous delivery lenalidomide (LLD) in chronic lymphocytic leukemia (CLL). Video, https://youtu.be/d8CHR7et5zs from Start to 7 minutes: Rodent Studies of PK, Safety and Tolerability of LLD in Healthy and SCID Mice by Dr Jamie Oliver Chief Medical Officer of Starton Therapeutics (https://startontx.com/). IMS/SMP-300 for mice or larger...

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1-channel infusion pump

SMP200

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