LC Platform Can Alter Established LC Methods

Waters’ ACQUITY Arc System is specifically engineered to respond to the needs of analytical scientists who called for a single LC platform that allows them to efficiently transfer, adjust or improve methods regardless of the LC platform on which they were originally developed.

To date, scientists working with established methods haven’t had an LC platform versatile enough to bridge the gap between HPLC and UPLC. With this system, and its enabling Arc Multi-flow path technology, scientists now have the ability to emulate the gradient dwell volume and mixing behavior of various LC systems.

By selecting the appropriate fluidic path, the system can easily emulate a variety of HPLC systems without altering the method’s gradient table, or provide UHPLC performance with the flip of a switch. In addition to replicating established HPLC assays without altering the gradient table, the system can enable improved chromatographic performance of methods by leveraging 2.5 to 2.7 um particle column technologies, as well as support previously developed applications on 3 to 5 um HPLC columns.