Whitepaper: HbA1c testing cabailities on the RX modena clinical chemistry analyser
The measurement of HbA1c is used in the long-term monitoring of diabetes mellitus. This assay should not be used in the diagnosis of diabetes mellitus or for day to day glucose monitoring. Diabetes Mellitus is a disease associated with poor glycaemic control. Numerous clinical studies, including the Diabetes Control and Complications Trial, have shown that diabetes related complications may be reduced by the long term monitoring and tight control of blood glucose levels. In the diabetic patient where blood glucose levels are abnormally elevated the level of HbA1c also increases, the reason for this is that HbA1c is formed by the non-enzymatic glycation of the N-terminus of the ß-chain of haemoglobin Ao.