MM-500 Motorized Micromanipulator— Multiple Experimental Scenarios Application

applied in patch clamp experiments and more experiments

Aiming to micromanipulators, only holding glass microelectrodes in patch clamp experiments comes to mind?

Now the MM-500 Motorized Micromanipulator offers much more than that. It can be used in combination with different syringe pumps to achieve nanoscale or microscale quantitative and fixed-speed injection or suction.

Applications of micromanipulation in patch clamp, microinjection, precision machinics will be introduced in details below.

1. Patch Clamp Experiment

What we can offer: By moving the glass microelectrode clamped on the amplifier probe, by selecting different recording modes (cell-attached, whole-cell mode, etc.), the microelectrode is tightly sealed with the cell membrane, and the signal on the cell membrane is recorded.

The scenarios are:

a. Ion channel related diseases research;

b. Research on ion channel function;

c. Active drug screening studies;

d. Research on the mechanism of drug;

e. Other related research

2. Microinjection experiment

2.1 MM-500 Motorized Micromanipulator & R480 Nanoliter Injection Pump

What we can offer: Nanoscale quantitative and constant-speed injection or suction is performed by moving the glass microelectrode clamped on the R480 nanoliter injection pump.

The scenarios are:

a. RNA microinjection of Xenopus oocytes;

b. Microinjection of zebrafish embryos;

c. Insect and protozoan egg cells, larvae, etc. injection (Drosophila, C. elegans);

d. Microinjection of mammalian cells;

e. Other related research

2.2 MM-500 Motorized Micromanipulator & KDS Legato 130 Microsyringe Pump

What we can offer: Micro-liter quantitative and constant-speed injection or suction is performed by moving the injection needle clamped on the KDS micro-injection pump.

The scenarios are:

a. Microinjection administration;

b. Intracranial virus or tracer injection;

c. Eyeball injection;

d. Other related research

3. Precision machinery

What we can offer: By moving the gripper, pressure tests can be performed on different materials, etc.

The scenarios are:

a. Microscale elastic modulus test of hydrogel(eg. AFM probe);

b. Performance test of biomimetic material in the mouth area of Nepenthes;

c. Other related research

To learn more about micromanipulator, click here.