Dental tissue regeneration solution

Bone graft and collagen membrane

Bonabone™ is a natural bone grafting material made from traceable bovine cancellous bone. Its component is Carbonated hydroxyapatite (CHAp). It is manufactured by adopting a unique multi-step temperature controlled (low-temperature) calcination and special degreasing and deproteinization purification technologies. There are no residues of chemical substances or organic substances. Compared with bone grafting material calcined at high temperature, it has better biocompatibility, ensuring the safety of clinical use.
Bonabone™ retains the carbonate substitution of natural cancellous bone, the crystal structure with low crystallinity, as well as the macroscopic and microscopic porous interconnected structures with gradients. Its
metabolic process is close to the metabolic pattern of the human bone matrix. It enables human osteoclasts to absorb Bonabone™ particles while maintaining the physiological spatial structure, thus achieving predictable physiological bone reconstruction, reducing long-term bone resorption and providing a better choice for clinical practice.

Bonamem™ is derived from natural porcine pericardium membrane. Using the decellularization process, it retains a complete three-dimensional porous structure of collagen and contains functional components such
as growth factors and adhesion proteins. Since the pericardium membrane must withstand the pressure of the heart muscles, fix the heart, and limit excessive expansion of the heart, it has extremely strong mechanical properties, as well as good softness, conformability, and hydrophilicity. It has good stability, which is beneficial for operation. Meanwhile, it also has a suitable degradation period of 3 to 6 months. Rich in bioactive substances, it can stimulate cellular responses and promote and induce tissue repair and regeneration. With a high porosity of 80%, it can achieve early vascularization and simultaneously promote the formation of new bone beneath the membrane. It is currently an extracellular matrix membrane with a relatively high cost-per-formance ratio.