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Featured Research Tools for Warburg Effect in Cancer Metabolism
Research tools for monoclonal rabbit antibodies
Cancer metabolism studies start with the observation of Warburg effect, which is a phenomenon that cancer tissues use glucose to generate lactate even in the presence of enough amount of oxygen. This phenomenon was once regarded as one of the prerequisites for the transformation of a differentiated cell into a proliferative cancer cell. However, the tricarboxylic acid (TCA) cycle, as the major source of energy for cells, still happen in most cancer cells to promote flux and tumor growth. In recent years, studies focusing on this topic also tried to figure out the relationship between the Warburg effect and other anabolic side pathways that support synthesis of nucleotides, lipids, and amino acids necessary for cancer cell proliferation.
