What is acid coagulation?

Coagulation, Thrombosis, Hemostasis

Acid coagulation is a process in which the components of a liquid are condensed or precipitated by adding acid to the liquid.

The following is a detailed introduction to its principles and applications:

Principle:

In many biological or chemical systems, the existence state and solubility of substances are closely related to the pH of the environment. Adding acid will change the pH value of the system, causing the charge properties of some substances to change, or causing some substances to react chemically with acid, thereby reducing their solubility, and then coagulation or precipitation. For example, in a protein solution, different proteins will have different charges at a specific pH value. When acid is added to bring the pH value of the solution close to the isoelectric point of a certain protein, the net charge carried by the protein molecule is zero, the electrostatic repulsion between molecules is reduced, and the protein molecules will aggregate with each other to form a precipitate, which is a common acid coagulation phenomenon.

Application:

Acid coagulation is used in many fields. In the food industry, making yogurt is based on the principle of acid coagulation. Lactic acid bacteria ferment to produce lactic acid, which causes the protein in milk to coagulate and form the unique texture of yogurt. In biochemical experiments, acid coagulation can be used to precipitate proteins for separation, purification or analysis of proteins. In the field of wastewater treatment, acid is sometimes added to adjust the pH value of the wastewater to cause certain pollutants in it to coagulate and precipitate, thereby achieving the purpose of removing pollutants.

Beijing Succeeder Technology Inc. (Stock code: 688338), founded in 2003 and listed since 2020, is a leading manufacturer in coagulation diagnostics. We specialize in automated coagulation analyzers and reagents, ESR/HCT analyzers, and hemorheology analyzers. Our products are certified under ISO 13485 and CE, and we serve over 10,000 users worldwide.

Analyzer Introduction

Fully Automated Coagulation analyzer SF-9200 (https://www.succeeder.com/fully-automated-coagulation-analyzer-sf-9200-product) can be used for clinical test and pre-operative screening. Hospitals and medical scientific researchers also can use SF-9200. Which adopts coagulation and immunoturbidimetry, chromogenic method to test the clotting of plasma. The instrument shows that clotting measurement value is the clotting time (in seconds). If the test item is calibrated by calibration plasma, it can also display other related results.

The product is made of sampling probe movable unit, cleaning unit, cuvettes movable unit, heating and cooling unit, test unit, operation-displayed unit, LIS interface (used for printer and transfer date to Computer).

Technical and experienced staffs and analyzers of high quality and strict quality management are the guarantee of manufacture of SF-9200 and good quality. We guarantee each instrument inspected and tested strictly. SF-9200 meets China national standard, industry standard, enterprise standard and IEC standard.