Ultima Multiphoton Microscope Systems

Multiphoton microscopy provides optical sectioning capabilities to depths of greater than 1mm at diffraction limit resolution. Compared to confocal, multiphoton microscopy allows deeper imaging into tissue, making it the technique of choice for thicker tissue specimens, such as brain slices or tumor or lymph node explants, as well is intravital imaging in small animal models.

In addition to multiphoton imaging, Bruker has pioneered the use of multiphoton techniques for photoactivation and photostimulation. Optical configurations allowing the use of fast pulsed IR lasers provide the ability to perform photoactivation and photostimulation with precise 3D localization. Our applications experience covers a wide range, including neuroscience, oncology, immunology, and cell biology, and our system and software options reflect what we have learned from the life science community.

Fully configurable multiphoton microscopes:

•Ultima IntraVital, Bruker''s flagship multiphoton system, is designed for high-speed live animal imaging, and includes an optional orbital nosepiece, a resonant scanner, and optogenetics modules.

•Ultima In Vitro is available as either an upright or an inverted microscope, with optional photoactivation, and electrophysiology recording.

•The Ultima family''s diverse options are designed for flexibility and configurability.