New PhysioFlow® Scientific Literature Review – 2026 Edition

Explore the clinical evidence supporting non-invasive haemodynamic assessment at rest and during exercise.

Manatec Biomedical is pleased to announce the release of the 2026 PhysioFlow® Scientific Literature Review, an updated compilation of peer-reviewed studies and scientific publications involving PhysioFlow Signal-Morphology Impedance Cardiography (SM-ICG).

With more than 25 years of clinical and research experience, PhysioFlow provides non-invasive assessment of central haemodynamics, both at rest and during exercise, offering valuable insights into cardiovascular function and adaptation to physiological stress.

The updated review brings together scientific evidence across a broad range of clinical and research applications, including cardiology, heart failure, cardiac rehabilitation, pulmonology, critical care, and human performance.

Particular attention is given to the assessment of haemodynamic responses during exercise, including changes in stroke volume, cardiac index, and contractility index. These measurements can complement conventional clinical investigations and cardiopulmonary exercise testing (CPET), helping researchers and clinicians better understand the mechanisms underlying exercise intolerance and functional improvement.

The review also includes methodological and reproducibility studies, providing a balanced overview of the capabilities and limitations of the technology.

Discover the scientific evidence behind PhysioFlow® and explore its applications in clinical practice and research.

Download the full 2026 Scientific Literature Review using the link below.