The development of proteolysis targeting chimera (PROTAC) molecules is at the forefront of modern drug discovery. The field has matured to the extent that first-generation compounds have progressed into clinic and proven efficacy. We are now in an era of competitive PROTAC drug discovery, where an ability to understand the design concepts, specialist assays and the requi...
Welcome to our second series of Ask an Expert! webinars. Back by popular demand, we're pleased to bring you a webinar dedicated to helping you get the best out of your Malvern Panalytical instrument. Whether you have questions about samples or sample prep, setting up an experiment or performing an analysis, feel free to submit a question so that we can deliver the inform...
As the situation has improved, we are pleased to inform you that Meling Biology & Medical will be participating in the 2022 Analitika Expo which will be held in Moscow from April 19th to 22nd, 2021. Our booth number: Crocus Expo IEC, Pavilion 3, Hall 13. You can find many cold chain products from Meiling. We are committed to helping fight the pandemic with our high-quali...
We were pleased to meet a lot of potential partners & customers in Korea while exhibiting Korea Lab 2021. The exhibition was one of the largest international exhibitions in Biotech & Life Sciences industries. We were very happy to show new product and the existing products once again! As a growing company every year, we continue to understand customers needs and develop...
Amorphous solid dispersions (ASDs) present a formulation option for poorly soluble drugs intended for oral administration. They work by molecularly dispersing the drug substance in a water-soluble polymer, thereby disrupting the intermolecular bonds that would otherwise form a crystal. Once the polymer dissolves, the drug molecule is also in solution and therefore availa...
Providing a wealth of data about protein characteristics, size-exclusion chromatography (SEC) plays a critical role in the characterization of biologics. However, this popularity of this technique can lead to bottlenecks developing and costs mounting. Are your samples getting held up as they wait for SEC analysis? Are your assay costs mounting due to sample volume requ...
A key challenge when designing compounds that target the central nervous system (CNS) is the prediction of blood-brain barrier (BBB) penetration. The BBB can hinder paracellular transport, so CNS drugs typically pass into the brain via transcellular permeation. However, this route can be challenged by issues with the efflux of the drug from within the cells, which can dr...
This session of ‘Ask an Expert!’ is all about semi-quantitative analysis with an Epsilon 4 ED-XRF spectrometer using Malvern Panalytical’s Omnian software package. After this webinar you will be able to make the best use of Omnian and get the best results for whatever sample is used. We will demonstrate how to optimize the spectra, make the best use of processing paramet...
There is increasing interest in Isothermal Titration Calorimetry (ITC) applications that require dissolving the binding partners in an organic solvent. These include studying guest-host chemical reactions, interactions involving nanoparticles, and characterizing normally insoluble materials. For successful results, the ITC experimental protocol with organic solvents requ...
Controlling solid form is a key concern from the moment lead compounds are crystallized, all the way through to commercial manufacture. And as a lead becomes a candidate molecule, it’s important to understand how its particles are distributed and how they behave. The particle size distribution and purity of an API are often controlling factors in how it moves, packs and ...
Tianlong invites you to the first event of 2022! Visit us at booth Z1.D49 at Medlab Middle East from 24 -27 January 2022. At this fair, you’ll see our integrated PCR lab solution. Our professionals will be delighted to discuss possible opportunities with you. We are looking forward to seeing you in Medlab 2022!
MEDICA 2021
Since the COVID-19 outburst, we stop the exhibition show abroad temperately. Choose to join the CMEF autumn is the aoog hoping and expectation we are looking for. We hope the virus pass fast and our life and business back to normal. We are with our best sincere to open a winder so that our customer can find us and hoping we can offer the best support for all of the frien...
Medlab Middle East is where you can feel the pulse of the medical laboratory industry. Discover innovative products, trending technology, infinite networking opportunities. Medlab Middle East 2022 Connections Experience – an online platform that will empower you with free access to the latest industry content and global networking opportunities. From 5 Jan - 28 Feb, gai...
Join pharmaceutical industry expert Maria Sobusiak to explore best practices for transferring laser diffraction particle sizing methods between teams, sites and instruments. As an active substance moves along the workflow, it may pass between various teams and even between different sites. When changes like this happen, it’s essential to perform an assessment of the rob...
Let's end a year full of webinars with something special. A webinar like we've never done before. To mark the 12 Days of Christmas, we’ll bring you insights into the world of laser diffraction from 12 of our experts from across the globe. These detail-loving geeks are always learning new things about how our technologies are used and this is their opportunity to share so...
Tianlong sincerely invites you to Medica 2021 and stop by our booth Hall 10, 10H34 to know more about Tianlong and our integrated PCR lab solution!
Tecna will be present at the COMPAMED fair in Düsseldorf from 15 to 18 November (Hall 14 / D58), the international leading trade fair for the supplier market for medical manufacturing. Discover our products and solutions designed for medical environment.
Setting meaningful and realistic specifications for a product’s material attributes is crucial in ensuring that the product behaves and performs as required. Within this, the particle size and particle size distribution of the ingredients and excipients present within a product’s formulation are often considered important. Why is this the case, and how do we know whether...
Mastersizer and the technique of laser diffraction are synonymous with particle sizing. Mastersizer leads the market for particle size analysis.It is a lynchpin in industries as diverse as cement manufacture, food formulation, and pharmaceutical development. It is the reliable analytical workhorse, delivering valuable data and insight to many thousands of users every d...
There are over 40 trainees from 19 different countries attending. Participants who complete the training workshop successfully will be issued a certificate from the Department of International Cooperation of the Chinese MOST(The Ministry of Science and Technology). Miconvey is honored to invite our customers to attend the training and help them improve their surgery skills.
We might be biased, but we see the impact of particle size everywhere! From the flavor of your morning coffee to the smoothness of your favorite chocolate, not forgetting how quickly you can charge your phone! For pharmaceuticals, the particle size distribution of both active ingredients and excipients is important throughout the development and production process. In...
In this webinar, senior formulation scientist Dr. Andrew Deacon, from Concept Life Sciences, will demonstrate the importance of deformulation or ‘reverse engineering’ to elucidate the analytical approaches that can be applied in the detection of active pharmaceutical ingredients (APIs) and excipients. Deacon will show how assessment of the physicochemical properties of A...
The Mastersizer 2000 laser diffraction particle size analyzer reaches the end of its supported life in April 2022. If you are a Mastersizer 2000 user, you need to act now to plan your upgrade and safeguard your method transfer activities.This is a great opportunity to verify approved methods for Mastersizer 2000 and plan its transfer to the Mastersizer 3000. During veri...
EKF Diagnostics announces that it will be exhibiting live & in person at Medica 2021 (Hall 3 Stand B71) for the first time in mainland Europe in two years. EKF’s presence at this show will give visitors the opportunity to catch up with its industry specialists face-to-face and see the recently launched STAT-Site® WB β-ketone and glucose handheld analyzer on its first pub...
Medica 2021 exhibition is coming up, which will start from November 15th to 18th in Dusseldorf, Germany. Tianlong will be happy to see you there and welcome to stop by our booth Hall 10, 10H34 to know more about Tianlong and our total PCR lab solutions. Sincerely welcome your arrival!
DATE: Fri Sep 24th, 2021 TIME：6:00AM(PDT) 3:00PM (GMT+2) 9:00PM(GMT+8) TOPIC 1 Electrostimulation of rat lateral hypothalamus to establish mania model and its future prospects LEARNING OBJECTIVES 1. What is the LHK animal model of mania? 2. Eliciting behavior through stimulation of specific regions using specific parameters. How far can we take this finding? 3. Measuri...
Introducing Malvern Panalytical's Empyrean series 3, the market's first intelligent X-ray diffractometer. Empyrean, is your trusted lab companion with automated batch sampling for solids, powders, thin films, single crystals whether in transmission or reflection mode. Pre-load your samples, step away to do more productive work. No need to any manual intervention to align...
Groenlandia Tech's presence at MEDICA 2021 fair Greenland Tech will attend as an exhibitor at this world-renowned event. The technology company will present Nuuk, the smart refrigerator that allows the shipment of biological samples, organs and drugs at a controlled temperature, as well as their complete traceability and impact control. MEDICA 2021 Main Topics: Focus o...
Immunotherapy is a powerful tool in the targeted treatment of a wide range of disease pathologies and the number of immunotherapy drugs in the discovery pipeline continues to grow. Approaches can include switching off or restoring balance to aberrant immune responses (such as those in autoimmune disease or allergy) or switching on beneficial immune responses (such as tho...
Is solid form characterization critical in your line of work, but you lack expertise in X-ray diffraction (XRD)? Do you need an efficient tool to support you with lead optimization? Do you need an easy way to validate the stability of solid form following processing? Join our webinar to find out how Malvern Panalytical’s solution for solid form screening and validation ...
In recent years, new developments in Size Exclusion Chromatography (SEC) have resulted in the introduction of Ultra-High-Performance Liquid Chromatography (UHPLC or UPLC®) for polymer applications. Waters ACQUITY Advanced Polymer Chromatography (APC™) is a breakthrough technology that provides SEC analyses of polymeric materials with higher resolution and higher speed th...
Liposomes and lipid nanoparticles (LNPs) are becoming established as leading materials for the encapsulation and in vivo delivery of a wide range of clinical materials, including drugs, therapeutic agents, mRNA and other APIs. This technology is now used for a wide range of applications, spanning vaccine development, nanomedicines and gene therapy. Optimizing LNP formula...
The Digital Pathology Virtual Summit's purpose is to illuminate the adoption of Digital Pathology, globally. Showcasing some of the greatest minds in Digital Pathology, the 2021 Digital Pathology Summit presents real-world experiences from renowned institutions, as well as the latest advances, including Artificial Intelligence, to guide you on your Digital Pathology jo...
THEME Course 3: The Potassium Channel Kv1.3 as a Therapeutic Target for Immunocytoprotection After Reperfusion LEARNING OBJECTIVES 1.The function of the voltage-gated potassium channel Kv1.3. 2.The Kv1.3 blocker PAP-1 and its effects. 3.Middle cerebral artery occlusion animal model in females and aged animals. 4.Microglia/macrophage activation and T cell infiltration af...
